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Alpha-Synuclein

Methods and Protocols
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Description

This volume provides the reader with detailed protocols that describe a variety of in vitro and in vivo techniques that study reductionist systems and human samples. The methods covered in this book explore a broad selection of topics such as functional aspects of alpha-synuclein biology, its lipid-interactions and misfolding, and functional deficits in cells and mice. Chapters also cover topics such as kinetic measurements of endocytosis and exocytosis in cultured neurons; electrochemiluminescence-based detection; yeast-based screens to target alpha-synuclein toxicity; mass-spectrometry of alpha-synuclein in rat cortical neurons; and expression and purification of untagged a-synuclein. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Alpha-Synuclein: Methods and Protocols is a valuable reference guide that aids researchers working on topics related to alpha-synuclein and its various aspects.
Release date Australia
February 18th, 2019
Audience
  • Professional & Vocational
Contributor
  • Edited by Tim Bartels
Edition
1st ed. 2019
Illustrations
55 Illustrations, color; 11 Illustrations, black and white; XII, 289 p. 66 illus., 55 illus. in color.
Pages
289
ISBN-13
9781493991235
Product ID
28766846

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