Ready for Ryzen™: Latest AMD socketTR4 for Threadripper™ processors.
5-Way Optimization: One-click, system-wide tuning, delivering optimized overclocks and intelligent cooling for CPU or GPU-intensive tasks.
Industry-leading cooling options: Comprehensive controls for fans and water pumps, via Fan Xpert 4 software or the acclaimed ASUS UEFI.
Next-gen connectivity: Onboard U.2, M.2 and front-panel USB 3.1 Gen 2 connector.
M.2 heatsink: Ultra-efficient heatsink reduces M.2 SSD temperatures by up to 20°C for unthrottled transfer speeds and enhanced reliability.
Aura Sync: Controllable onboard RGB lighting easily syncs with an ever-growing portfolio of Aura Sync-capable hardware.

Prime
ASUS Prime X399-A is the EATX motherboard that's been expertly engineered for professional content creators and power users who work hard by day and play harder by night. This powerful, innovative board puts a friendly face on advanced enthusiast controls, enabling you to maximize performance, cooling and personalization with ease. So, if you live to create, explore, and to push the boundaries, look no further than the Prime X399-A.

5-Way Optimization
One-click overclock and cooling, done!
One click takes care of all that complex tuning. ASUS 5-Way Optimization makes your PC smart. It dynamically optimizes essential aspects of the system, providing overclocking and cooling profiles that are tailored for your rig.

An automated tuning utility that optimizes overclocking and cooling profiles for your unique system configuration.
Fans stay whisper-quiet for everyday computing, and deliver optimal airflow when the system is crunching through CPU or GPU-intensive tasks.
All-new stress test that allows users to optimize and overclock for CPU or memory-centric workloads.

Media-acclaimed UEFI BIOS
The smoothest, slickest mouse-controlled graphical BIOS has been improved to make it even more appealing. Whether you're a PC novice or a seasoned overclocker, the EZ and Advanced Modes help you find your way, quickly and easily.

EZ Tuning Wizard
Quickly apply a CPU overclock to improve system performance

Make your memory go faster
Prime X399-A is engineered to support quad-channel memory kits rated up to a staggering DDR4 3600MHz, allowing you to get the best performance from the X399 platform. We've worked with all major DDR4 memory vendors to help ensure compatibility, so you're assured the best compatibility.

M.2
Speed up with onboard M.2 up to 32Gbps
With x4 PCI Express 3.0/2.0 bandwidth, M.2 supports up to 32Gbps data-transfer speeds. It is the perfect choice for an operating system or application drive, providing fast access to data.

M.2 heatsink
Keep your SSD cooler
Prime X399-A has an ultra-efficient heatsink to reduce M.2 SSD temperatures by up to 20°C — and that means optimal storage performance and improved SSD longevity.

U.2 connector
Join the NVMe revolution
The revolutionary specification that lets your SSDs scream at top speed. Just attach your chosen drive to with plug-and-play ease to experience data-transfer speeds of up to 32Gbps — and free up a PCIe slot for another expansion card.

USB 3.1 Gen 2 front-panel connector
Future-proof connectivity
Prime X399-A's front panel USB 3.1 connector is ready for next-gen PC cases and devices.

USB 3.1 Gen 2 Type-A & Type-C
Ultimate-speed 10Gbps with USB 3.1 onboard
With backward-compatible USB 3.1 Gen 2 Type-A™ and reversible USB 3.1 Gen 2 Type-C™ ports, you'll experience ultimate connection flexibility and blazing data-transfer speeds of up to 10Gbps.

Intel Ethernet
More throughput, less CPU usage
Prime X399-A features the latest Intel Ethernet. Intel's LAN has the advantage of reducing CPU overhead and offering exceptionally high TCP and UDP throughput for faster, smoother data transfer.

Multi-GPU support
With support for both NVIDIA® SLI™ and AMD CrossFireX™ 2/3-WAY configurations, Prime X399-A motherboard enables multi-GPU setups so you can harness the full power of the latest graphics technologies to drive games at 4K and beyond.

SafeSlot
Protect your graphics card investment
SafeSlot* is the PCIe slot reinvented by ASUS and engineered to provide superior retention and shearing resistance. Manufactured in a single step using a new insert-molding process, SafeSlot integrates the slot with fortifying metal for an inherently stronger slot, which is then firmly anchored to the PCB through additional solder points.

Outstanding audio
Realtek codec and unique design features for pristine, powerful audio

Prime X399-A utilizes a unique audio codec designed in close collaboration with Realtek — the Realtek S1220A. It also features an unprecedented 120dB signal-to-noise ratio for the stereo line-out and a 113dB SNR for the line-in, providing pristine audio quality. Additionally, a new impedance-sensing circuit automatically adjusts gain to ensure the optimal volume range for your headphones.

DTS Headphone:XTM
Surround sound, to go
Immersive 3D surround-sound technology provides incredible audio experiences.

Crystal Sound 3
Flawless audio that makes you part of the game
Power pre-regulator
Reduces power-input noise to ensure consistent performance.

Audio shielding
Separates analog/digital signal domains, significantly reducing multi-lateral interference.

Separate layer for left and right tracks
Ensures minimal crosstalk between audio paths.
Integrated amplifier
Capable of driving high-impedance headphones, without rolling-off high or low frequencies.

De-pop circuit
Reduces start-up popping noise to all audio outputs.

Premium Japanese-made audio capacitors
Premium parts provide an immersive sound signature, with exceptional fidelity.

Aura Sync
Outshine your competition
A well-tuned enthusiast system deserves a matching aesthetic. ASUS Aura offers full RGB lighting control with a variety of functional presets for the built-in RGB LEDs as well as strips connected to the onboard RGB header.* And it can all be synced with an ever-growing portfolio of Aura-capable ASUS hardware.

Exclusive 3D mount for easy installation
Make it your own
Dedicated 3D mounts on the motherboard makes fitting 3D-printed parts easy. Using the same screws as M.2 drives and standard motherboard mounting holes, you can easily add nameplates and cable covers.

Specifications

CPU
AMD Socket TR4 for AMD Ryzen™ Threadripper™ Processors

• Refer to www.asus.com for CPU support list

Chipset
AMD X399

Memory
AMD Ryzen™ Threadripper™ Processors
8 x DIMM, Max. 128GB, DDR4 3200(O.C­.)/3000(O.C.)/2800(O­.C.)/2666/2400­/2133 MHz Non-ECC, Un-buffered Memory
** Refer to www.asus.com for the Memory QVL (Qualified Vendors Lists).

Multi-GPU Support
Supports NVIDIA® Quad-GPU SLI™ Technology
Supports NVIDIA® 3-Way SLI™ Technology
Supports NVIDIA® 2-Way SLI™ Technology
Supports AMD Quad-GPU CrossFireX™ Technology
Supports AMD 3-Way CrossFireX™ Technology
Supports AMD 2-Way CrossFireX Technology

Expansion Slots
AMD Ryzen™ Threadripper™ Processors
4 x PCIe 3.0 x16 (single@x16, dual@x16/x16, triple@x16/x16/x8 mode)
AMD X399 chipset
1 x PCIe 2.0 x4 (max at x4 mode)
1 x PCIe 2.0 x1

Storage
AMD Ryzen™ Threadripper™ Processors :
1 x M.2 Socket 3, with M key, type 2242/2260/2280 storage devices support (SATA & PCIE 3.0 × 4 mode)
1 x M.2 Socket 3, with M key, type 2242/2260/228­0/22110 storage devices support (SATA & PCIE 3.0 × 4 mode)
1 x U.2 port
AMD X399 chipset :
6 x SATA 6Gb/s port(s),
Support Raid 0, 1, 10

LAN
Intel® I211-AT
ASUS Turbo LAN Utility
ASUS LAN Guard

Audio
Realtek® ALC S1220A 8-Channel High Definition Audio CODEC featuring Crystal Sound 3

• Impedance sense for front and rear headphone outputs
• Internal audio Amplifier to enhance the highest quality sound for headphone and speakers
• Supports : Jack-detection, Multi-streaming, Front Panel Jack-retasking
• High quality 120 dB (Line-out at rear) and 113 dB SNR recording input (Line-in)

Audio Feature :

• DTS Connect
• DTS Headphone:X
• Optical S/PDIF out port(s) at back panel
• Audio Shielding: Ensures precision analog/digital separation and greatly reduced multi-lateral interference
• Dedicated audio PCB layers: Separate layers for left and right channels to guard the quality of the sensitive audio signals
• Premium Japanese-made audio capacitors: Provide warm, natural and immersive sound with exceptional clarity and fidelity
• Unique de-pop circuit: Reduces start-up popping noise to audio outputs
• EMI protection cover to prevent electrical noise to affect the amplifier quality

Separate layer for left and right track, ensuring both sound deliver equal quality

USB Ports
AMD Ryzen™ Threadripper™ Processors :
8 x USB 3.1 Gen 1 port(s) (8 at back panel, , Type-A)
AMD X399 chipset :
1 x USB 3.1 Gen 2 port(s) (1 at mid-board)
AMD X399 chipset :
4 x USB 3.1 Gen 1 port(s) (4 at mid-board)
AMD X399 chipset :
4 x USB 2.0 port(s) (4 at mid-board)
ASMedia® USB 3.1 Gen 2 controller :
2 x USB 3.1 Gen 2 port(s) (Type-A + USB Type-CTM)

Special Features
OC Design – ASUS PRO Clock Technology

• Full BCLK range for extreme overclocking performance

ASUS Dual Intelligent Processors 5-Way Optimization by Dual Intelligent Processors 5 :

• 5-Way Optimization tuning key perfectly consolidates TPU, EPU, DIGI+ VRM, Fan Expert 4, and Turbo App

AURA :

• Aura RGB Strip Headers
• Aura Lighting Effects Synchronization with compatible ASUS ROG devices

ASUS Exclusive Features :

• USB BIOS Flashback
• AI Suite 3
• Ai Charger
• Onboard Button : Power
• ASUS UEFI BIOS EZ Mode featuring friendly graphics user interface
• Turbo LAN
• Crystal Sound 3
• PC Cleaner

ASUS Quiet Thermal Solution :

• Stylish Design Heat-pipe solution
• Stylish Fanless Design with M.2 Heat-sink solution
• ASUS Fan Xpert 4

ASUS EZ DIY :

• ASUS EZ Flash 3
• ASUS USB BIOS Flashback
• ASUS UEFI BIOS EZ Mode
• Multi-language BIOS

ASUS Q-Design :

• ASUS Q-Shield
• ASUS Q-Code
• ASUS Q-LED (CPU, DRAM, VGA, Boot Device LED)
• ASUS Q-Slot
• ASUS Q-DIMM
• ASUS Q-Connector

Gaming Aesthetics :

• 3D printing friendly
• AURA-RGB Lighting

M.2 and U.2 Onboard (The Latest Transfer Technology with up to 32Gb/s Data-transfer Speeds for M.2 and U.2)

Back I/O Ports
1 x LAN (RJ45) port(s)
2 x USB 3.1 Gen 2 (teal blue)Type-A + USB Type-CTM
8 x USB 3.1 Gen 1 (blue)
1 x Optical S/PDIF out
5 x Audio jack(s)
1 x USB BIOS Flashback Button(s)

Internal I/O Ports
1 × 3-pin Cover fan (COV_FAN) connector
1 x Q_Code
1 x U.2 port
2 x RGB Header(s)
2 x USB 3.1 Gen 1 connector(s) support(s) additional 4 USB 3.1 Gen 1 port(s)
2 x USB 2.0 connector(s) support(s) additional 4 USB 2.0 port(s)
1 x M.2 Socket 3 with M key, type 2242/2260/2280 storage devices support (SATA & PCIE 3.0 × 4 mode)
1 x M.2 Socket 3 with M key, type 2242/2260/228­0/22110 storage devices support (SATA & PCIE 3.0 × 4 mode)
6 x SATA 6Gb/s connector(s)
1 x M.2_FAN connector
1 x CPU Fan connector(s)
1 x CPU OPT Fan connector(s)
3 x Chassis Fan connector(s)
1 x AIO_PUMP connector
1 x W_PUMP+ connector
1 × 24-pin EATX Power connector(s)
1 × 8-pin ATX 12V Power connector(s)
1 × 4-pin ATX 12V Power connector(s)
1 x Front panel audio connector(s) (AAFP)
1 x System panel(s)
1 × 5-pin EXT_FAN(Extension Fan) connector
1 x Thermal sensor connector(s)
1 x Power-on button(s)
1 x Clear CMOS button(s)
1 x USB 3.1 Gen 2 front panel connector

Accessories
User's manual
ASUS Q-Shield
1 x Vertical M.2 bracket set
4 x SATA 6Gb/s cable(s)
1 x M.2 Screw Package
1 x Supporting DVD
1 x SLI HB BRIDGE(2-WAY-M)
1 x Q-Connector

BIOS
128 Mb Flash ROM, UEFI AMI BIOS, PnP, WfM2.0, SM BIOS 3.0, ACPI 6.1, Multi-language BIOS, ASUS EZ Flash 3, CrashFree BIOS 3, F11 EZ Tuning Wizard, F6 Qfan Control, F3 My Favorites, Last Modified log, F12 PrintScreen and ASUS DRAM SPD (Serial Presence Detect) memory information

Manageability
WfM 2.0, DMI 3.0, WOL by PME, PXE

Operating System
Windows® 10 64-bit
Form Factor
Extended ATX Form Factor
12 inch x 10.6 inch ( 30.5 cm x 26.9 cm )