Vanadium is named after Vanadis, the most aristocratic of Norse goddesses, who symbolizes beauty and fertility - essential features of vanadium chemistry. It is a ubiquitous trace element, with a surprising range of biological functions. In "Bioinorganic Vanadium Chemistry", Dieter Rehder addresses the major aspects of vanadium chemistry related to living organisms and the mutual impact between biological and inorganic vanadium chemistry.Topics covered include: the history, natural occurrence, distribution and impact of vanadium; inorganic aspects of the function of vanadium in biological systems; interaction of aqueous vanadate and vanadyl with biogenic ligands; vanadium coordination compounds; the vanadium-carbon bond; methods of characterization of biogenic and model vanadium systems (EPR and ENDOR for oxovanadium(IV); 51V NMR for vanadium(V); XAS); vanadium in ascidians and polychaeta worms; the concentration of vanadium in the form of amavadin by Amanita mushrooms; vanadate-dependent haloperoxidases; vanadium and the nitrogen cycle; vanadate as energizer for bacteria, and vanadophores; medicinal aspects including the anti-diabetic potential of vanadium compounds; interaction of vanadium with proteins and protein substrates; and, vanadium and phosphate-metabolizing enzymes.
"Bioinorganic Vanadium Chemistry" conveys the essential aspects of vanadium bioinorganic chemistry, making this book a valuable complement to more general bioinorganic chemistry texts and more specialized topical reviews for researchers and students alike.
Table of Contents
Preface1. Introduction and Background1.1. History1.2. Occurrence, Distribution and Impact2. Inorganic and Coordination Compounds of Vanadium2.1. Inorganic Aspects of the Function of Vanadium in Biological Systems2.2. Interaction of Aqueous Vanadate and Vanadyl with Biogenic Ligands2.3. Vanadium Coordination Compounds2.4. The Vanadium-Carbon Bond3. Physico-chemical methods for the characterisation of native and model vanadium compounds3.1. 51V NMR Spectroscopy3.2. NMR of Other Nuclei3.3. EPR Spectroscopy3.4. ESEEM and ENDOR3.5. Optical Spectroscopies3.6. X-ray absorption spectroscopy4. Naturally Occurring Vanadium Compounds4.1 Vanadium in Ascidians and Polychaeta Worms4.2. Amavadin4.3. Vanadate-Dependent Haloperoxidases4.4. Vanadium and the Nitrogen Cycle4.5. Vanadate as Energiser for Bacteria, and Vanadophores5. Inferences of Vanadium Compounds with Cellular Functions5.1. Medicinal aspects5.2. Interaction of vanadium with proteins and protein substratesEpilogue