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Biomarkers in Breast Cancer
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Biomarkers in Breast Cancer

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Description

Expert laboratory and clinical researchers from around the world review how to design and evaluate studies of tumor markers and examine their use in breast cancer patients. The authors cover both the major advances in sophisticated molecular methods and the state-of-the-art in conventional prognostic and predictive indicators. Among the topics discussed are the relevance of rigorous study design and guidelines for the validation studies of new biomarkers, gene expression profiling by tissue microarrays, adjuvant systemic therapy, and the use of estrogen, progesterone, and epidermal growth factor receptors as both prognostic and predictive indicators. Highlights include the evaluation of HER2 and EGFR family members, of p53, and of UPA/PAI-1; the detection of rare cells in blood and marrow; and the detection and analysis of soluble, circulating markers.
Release date Australia
December 1st, 2010
Audience
  • Professional & Vocational
Contributors
  • Edited by Daniel F. Hayes
  • Edited by Giampietro Gasparini
Edition
Softcover reprint of hardcover 1st ed. 2006
Illustrations
22 Illustrations, black and white; XII, 342 p. 22 illus.
Pages
342
Dimensions
152x229x18
ISBN-13
9781617374364
Product ID
9985723

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