Cancer Immunotherapy at the Crossroads

Name: Cancer Immunotherapy at the Crossroads
SKU: 21845186
Price: 414.99 AUD
Availability: InStock

How Tumors Evade Immunity and What Can Be Done

Format:

Paperback / softback

Series:

Current Clinical Oncology

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Description

Leading investigators and clinicians detail the different mechanisms used by tumors to escape and impair the immune system and then spell out possible clinical strategies to prevent or reverse tumor-induced immune dysfunction. The authors review the mechanisms of immune dysfunction and evasion mechanisms in histologically diverse human tumors, focusing on tumor-induced molecular defects in T cells and antigen-presenting cells (dendritic cells and tumors), that may serve as biomarkers for patient prognosis. They discuss the means by which these immune functions may be protected or restored in order to more effectively support the process of tumor rejection in situ. Cutting-edge techniques are outlined with the capacity to monitor the strength and quality of patients' immune responses using immunocytometry, MHC-peptide tetramers combined with apoptosis assay, ELISPOT assay, and detection of MHC-TAA peptide complexes on tumor cells.

Release date Australia

August 2nd, 2012

Audience

Professional & Vocational

Contributors

Edited by James H. Finke
Edited by Ronald M. Bukowski

Edition

Softcover reprint of the original 1st ed. 2004

Illustrations

XVII, 386 p.

Pages

386

Series

Current Clinical Oncology

Dimensions

152x229x21

ISBN-13

9781468498448

Product ID

21845186

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Cancer Immunotherapy at the Crossroads

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