Recentyearshaveseentheadventanddevelopmentofmanydevicesabletorecordand storeaneverincreasingamountofinformation. Thefastprogressofthesetechnologies is ubiquitousthroughoutall ?elds of science and applied contexts, ranging from medicine,biologyandlifesciences,toeconomicsandindustry. Thedataprovided bytheseinstrumentshavedifferentforms:2D-3Dimagesgeneratedbydiagnostic medicalscanners,computervisionorsatelliteremotesensing,microarraydataand genesets,integratedclinicalandadministrativedatafrompublichealthdatabases, realtimemonitoringdataofabio-marker,systemcontroldatasets. Allthesedata sharethecommoncharacteristicofbeingcomplexandoftenhighlydimensional. Theanalysisofcomplexandhighlydimensionaldataposesnewchallengesto thestatisticianandrequiresthedevelopmentofnovelmodelsandtechniques,fueling manyfascinatingandfastgrowingresearchareasofmodernstatistics.
Anincomplete listincludes for example: functionaldata analysis, that deals with data having a functionalnature,suchascurvesandsurfaces;shapeanalysisofgeometricforms,that relatestoshapematchingandshaperecognition,appliedtocomputationalvisionand medicalimaging;datamining,thatstudiesalgorithmsfortheautomaticextraction ofinformationfromdata,elicitingrulesandpatternsoutofmassivedatasets;risk analysis,fortheevaluationofhealth,environmental,andengineeringrisks;graphical models,thatallowproblemsinvolvinglarge-scalemodelswithmillionsofrandom variableslinkedincomplexwaystobeapproached;reliabilityofcomplexsystems, whoseevaluationrequirestheuseofmanystatisticalandprobabilistictools;optimal designofcomputersimulationstoreplaceexpensiveandtimeconsumingphysical experiments. Thecontributionspublishedinthisvolumearetheresultofaselectionbasedonthe presentations(aboutonehundred)givenattheconference"S. Co. 2009:Complexdata modelingandcomputationallyintensivemethodsforestimationandprediction",held ? atthePolitecnicodiMilano. S. Co. isaforumforthediscussionofnewdevelopments ? September14-16,2009. Thatof2009isitssixthedition,the?rstonebeingheldinVenice in1999.
VI Preface andapplicationsofstatisticalmethodsandcomputationaltechniquesforcomplexand highlydimensionaldatasets. Thebookisaddressedtostatisticiansworkingattheforefrontofthestatistical analysisofcomplexandhighlydimensionaldataandoffersawidevarietyofstatistical models,computerintensivemethodsandapplications. Wewishtothankallassociateeditorsandrefereesfortheirvaluablecontributions thatmadethisvolumepossible. MilanandVenice,May2010 PietroMantovan PiercesareSecchi Contents Space-timetextureanalysisinthermalinfraredimagingforclassi?cation ofRaynaud'sPhenomenon GrazianoAretusi,LaraFontanella,LuigiIppolitiandArcangeloMerla...1 Mixed-effectsmodellingofKevlar?brefailuretimesthroughBayesian non-parametrics RaffaeleArgiento,AlessandraGuglielmiandAntonioPievatolo...13 Space?llingandlocallyoptimaldesignsforGaussianUniversalKriging AlessandroBaldiAntogniniandMaroussaZagoraiou...27 Exploitation,integrationandstatisticalanalysisofthePublicHealth DatabaseandSTEMIArchiveintheLombardiaregion PietroBarbieri,Niccolo'Grieco,FrancescaIeva,AnnaMariaPaganoniand PiercesareSecchi...41 Bootstrapalgorithmsforvarianceestimationin PSsampling AlessandroBarbieroandFulviaMecatti...5
7 FastBayesianfunctionaldataanalysisofbasalbodytemperature JamesM. Ciera...71 AparametricMarkovchaintomodelage-andstate-dependentwear processes MassimilianoGiorgio,MaurizioGuidaandGianpaoloPulcini...85 CasestudiesinBayesiancomputationusingINLA SaraMartinoandHav ? ardRue...99 Agraphicalmodelsapproachforcomparinggenesets M. So?aMassa,MonicaChiognaandChiaraRomualdi...115 VIII Contents Predictivedensitiesandpredictionlimitsbasedonpredictivelikelihoods PaoloVidoni...123 Computer-intensiveconditionalinference G. AlastairYoungandThomasJ. DiCiccio...137 MonteCarlosimulationmethodsforreliabilityestimationandfailure prognostics EnricoZio...151 ListofContributors AlessandroBaldiAntognini JamesM. Ciera DepartmentofStatisticalSciences DepartmentofStatisticalSciences UniversityofBologna UniversityofPadova Bologna,Italy Padova,Italy ThomasJ. DiCiccio GrazianoAretusi DepartmentofSocialStatistics DepartmentofQuantitativeMethods CornellUniversity andEconomicTheory Ithaca,USA UniversityG. d'Annunzio Chieti-Pescara,Italy LaraFontanella DepartmentofQuantitativeMethods RaffaeleArgiento andEconomicTheory CNRIMATI UniversityG. d'Annunzio Milan,Italy Chieti-Pescara,Italy MassimilianoGiorgio PietroBarbieri DepartmentofAerospace Uf?
cioQualita' andMechanicalEngineering CernuscosulNaviglio,Italy SecondUniversityofNaples Aversa(CE),Italy AlessandroBarbiero DepartmentofEconomics Niccolo'Grieco BusinessandStatistics A. O. NiguardaCa'Granda UniversityofMilan Milan,Italy Milan,Italy MaurizioGuida MonicaChiogna DepartmentofElectrical DepartmentofStatisticalSciences andInformationEngineering UniversityofPadova UniversityofSalerno Padova,Italy Fisciano(SA),Italy X ListofContributors AlessandraGuglielmi AntonioPievatolo DepartmentofMathematics CNRIMATI PolitecnicodiMilano Milan,Italy Milan,Italy GianpaoloPulcini alsoaf?liatedtoCNRIMATI,Milano IstitutoMotori NationalResearchCouncil(CNR) FrancescaIeva Naples,Italy MOX-DepartmentofMathematics PolitecnicodiMilano ChiaraRomualdi Milan,Italy DepartmentofBiology UniversityofPadova LuigiIppoliti Padova,Italy DepartmentofQuantitativeMethods andEconomicTheory H?avardRue UniversityG. d'Annunzio DepartmentofMathematicalSciences Chieti-Pescara,Italy NorwegianUniversityforScience andTechnology SaraMartino Trondheim,Norway DepartmentofMathematicalSciences NorwegianUniversityforScience PiercesareSecchi andTechnology MOX-DepartmentofMathematics Trondheim,Norway PolitecnicodiMilano Milan,Italy M.
So?aMassa DepartmentofStatisticalSciences PaoloVidoni UniversityofPadova DepartmentofStatistics Padova,Italy UniversityofUdine Udine,Italy FulviaMecatti DepartmentofStatistics G.
Author Biography:
Pietro Mantovan has been Professor of Statistics since 1986 at the University Ca' Foscari of Venezia, Italy, where he has served as coordinator of research units, head of the Departement of Statistics, and Dean of the Faculty of Economics. He has written several articles, monographs and textbooks on classical and Bayesian methods for statistical inference. His recent research interests focus on Bayesian methods for learning and prediction, statistical perturbation models for matrix data, dynamic regression with covariate errors, parallel algorithms for system identification in dynamic models, on line monitoring and forecasting of environmental data, hydrological forecasting uncertainty assessment, and robust inference processes. Piercesare Secchi is Professor of Statistics at MOX since 2005 and Director of the Department of Mathematics at the Politecnico di Milano. He got a Doctorate in Methodological Statistics from the University of Trento in 1992 and a PhD in Statistics from the University of Minnesota in 1995. He has written several papers on stochastic games and on Bayesian nonparametric predictive inference and bootstrap techniques. His present research interests focus on statistical methods for the exploration, classification and analysis of high dimensional data, like functional data or images generated by medical diagnostic devices or by remote sensing. He also works on models for Bayesian inference, in particular those generated by urn schemes, on response adaptive designs of experiments for clinical trials and on biodata mining. He is PI of different projects in applied statistics and coordinator of the Statistical Unit of the Aneurisk project.
