Even though we own both, I have found that we play Crabs Adjust Humidity more than we play CAH.
While CAH is great (don't get me wrong, its a fantastic game), I (and people I play with) have found that Crabs Adjust Humidity has a bit more smutty, gross, and random humour. Rather than mostly focusing on recent events, or shock laughs. There is still a lot of cards similar to the style of CAH, but if you are looking for a few more ‘out there’ cards, then go for this :)