Excerpt from Division of Cancer, Biology and Diagnosis, Vol. 2: 1986 Annual Report; October 1, 1985-September 30, 1986 The kinds of information developed in the Tumor Biology Program provide a foundation for and relate directly or indirectly to nearly every other program area within the National Cancer Institute. The importance of basic tumor biology research to the National Cancer Plan is reflected by the large $89 million commitment of the nci to this program area in FY 1986. (see Budget Table.) Complete listings and summaries of all grants supported by the Tumor Biology Program are included in the attached Appendices. Scientific progress in the area of tumor biology is developing at a remarkable pace. There is no doubt that dna recombinant technology continues to be the centerpiece of basic cancer biology research. This technology combined with other methods for introducing foreign genes into cells, especially by transfection and microinjection, has introduced experimental approaches which are yielding insightful results explaining the nature of the changes in normal cells which lead to uncontrolled growth and spread of cancer cells. In addition, newer technologies involving transgenic mice and anti sense messenger rna.are likely to yield even more powerful experimental approaches for delving into previously intransigent areas of cancer research. The following report selectively reviews areas in which progress has been exceptional and in which there is considerable promise for future research. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.