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Fibrous Proteins: Structures and Mechanisms

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Fibrous Proteins: Structures and Mechanisms

Format

Hardback

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Fibrous Proteins: Structures and Mechanisms
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Description

This book provides the readers with an up-to-date review of the design, structure and function of a representative selection of fibrous proteins in both health and disease. The importance of the α-helical coiled coil, a conformational motif based on the heptad repeat in the amino acid sequence of all α-fibrous proteins (and parts of some globular proteins) is underlined by three Chapters devoted to its design, structure, function and topology. Specific proteins covered in the text and which depend on the coiled coil for their structure and function, include the intermediate filament proteins, tropomyosin, myosin, paramyosin, fibrin and members of the spectrin superfamily. Also described are fibrous proteins based on the ss-pleated sheet and collagen conformations. Recombinant structural proteins, especially of silk and collagen, are discussed in the context of developing new biomaterials with varied applications. Established researchers and postgraduate students in the fields of protein chemistry, biochemistry and structural biophysics will find Fibrous Proteins: Structures and Mechanisms to be an invaluable collection of topical reviews that describe the basic advances made in the field of fibrous proteins over the past decade. This book, written by recognized authorities in the field, provides a clear account of the current status of fibrous protein research and, in addition, establishes the basis for deciding the most appropriate directions for future activity, including the applications of protein engineering and the commercial exploitation of new biomaterials.
Release date Australia
January 25th, 2017
Contributors
Edited by David A D Parry Edited by John M Squire
Country of Publication
Switzerland
Edition
1st ed. 2017
Illustrations
123 Illustrations, color; 31 Illustrations, black and white; VIII, 629 p. 154 illus., 123 illus. in color.
Imprint
Springer International Publishing AG
Pages
629
ISBN-13
9783319496726
Product ID
26206965

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