Genomic Instability and Cancer Metastasis

Name: Genomic Instability and Cancer Metastasis
SKU: 22794878
Price: 266.99 AUD
Availability: InStock

Mechanisms, Emerging Themes, and Novel Therapeutic Strategies

Format:

Hardback

Series:

Cancer Metastasis: Biology and Treatment

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Description

Metastasis is the primary cause of mortality associated with cancer, and tumor genomic heterogeneity is a likely source for the cells that support cancer progression, resistance to therapy, and disease relapse. This book connects cancer metastasis with genomic instability in a comprehensive manner. Section 1 outlines the fundamental mechanisms responsible for these cellular and tissue phenotypes. Section 2 discusses in silico, in vitro, and in vivo models used for the experimental study of these processes. Section 3 reviews emerging themes (ex., microenvironment, mechanotransduction, and immunomodulation), and Section 4 highlights new therapeutic approaches to overcome the unique challenges presented by the heterogeneous and metastatic tumor. This book is intended for undergraduates and postgraduates with an interest in the areas of medicine, oncology, and cancer biology as well as for the content expert searching for thorough reviews of current knowledge in these areas.

Release date Australia

December 16th, 2014

Audiences

Postgraduate, Research & Scholarly
Professional & Vocational
Undergraduate

Contributors

Edited by Cal Roskelley
Edited by Chris Maxwell

Illustrations

18 Illustrations, color; 1 Illustrations, black and white; X, 247 p. 19 illus., 18 illus. in color.

Pages

247

Series

Cancer Metastasis: Biology and Treatment

Dimensions

155x235x16

ISBN-13

9783319121352

Product ID

22794878

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Genomic Instability and Cancer Metastasis

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