This book has so closely matched the requirements of itsreadership over the years that it has become the first choice forchemists worldwide. Heterocyclic chemistry comprises at least half of all organicchemistry research worldwide. In particular, the vast majority oforganic work done in the pharmaceutical and agrochemical industriesis heterocyclic chemistry. The fifth edition of Heterocyclic Chemistry maintains theprincipal objective of earlier editions to teach thefundamentals of heterocyclic reactivity and synthesis in a way thatis understandable to second- and third-year undergraduate chemistrystudents. The inclusion of more advanced and current material alsomakes the book a valuable reference text for postgraduate taughtcourses, postgraduate researchers, and chemists at all levelsworking with heterocyclic compounds in industry.
Fully updated and expanded to reflect important 21stcentury advances, the fifth edition of this classic text includesthe following innovations: * Extensive use of colour to highlight changes in structure andbonding during reactions * Entirely new chapters on organometallic heterocyclic chemistry,heterocyclic natural products, especially in biochemical processes,and heterocycles in medicine * New sections focusing on heterocyclic fluorine compounds,isotopically labeled heterocycles, and solid-phase chemistry,microwave heating and flow reactors in the heterocycliccontext Essential teaching material in the early chapters is followed byshort chapters throughout the text which capture the essence ofheterocyclic reactivity in concise resumes suitable asintroductions or summaries, for example for examinationpreparation. Detailed, systematic discussions cover the reactivityand synthesis of all the important heterocyclic systems. Originalreferences and references to reviews are given throughout the text,vital for postgraduate teaching and for research scientists.Problems, divided into straightforward revision exercises, and morechallenging questions (with solutions available online), help thereader to understand and apply the principles of heterocyclicreactivity and synthesis.
John Joule is Emeritus Professor in the School of Chemistry,The University of Manchester, UK Keith Mills spent 25 years in the Medicinal Chemistry andDevelopment Chemistry departments at GlaxoSmithKline, Stevenage,UK, and is now an independent consultant.