Prof. Vincenzo Denaro has been Full Professor in orthopaedic surgery and Dean at the University Campus Bio-Medico of Rome, and is one of the leading spine surgeons in Italy. His training included Professor Boni in Pavia, Professor Roy-Camille at the Hopital Pitie Salpetriere in Paris, and Prof. Macnab in Toronto. Being one of the founder members of the Cervical Spine Research Society of Europe, he has been President of the Italian Spine Society. His main fields of interest include the management of patients affected by Spinal and Tumor diseases. He is co-author of the National Guidelines on the management of bone metastases of the Italian Orthopaedic Society (S.I.O.T.), and of the Italian Association of Medical Oncology (A.I.O.M). He is author of more than 300 papers and book chapters, and has edited two books. Dr. Alberto Di Martino is Assistant Professor in orthopaedics and trauma surgery at University Campus Bio-Medico of Rome. His main fields of interests include spine andtumor surgery, and basic research. He has a PhD in tissue regeneration in Orthopaedics, and in currently involved in the osteoncology unit at the University Campus Bio-Medico of Rome. His training include a Spine research fellowship at Thomas Jefferson University and the Rothman Institute of Philadelphia (USA), and is currently involved in the Spine and Oncology programs with Prof. Vincenzo Denaro at the University Campus Bio-Medico of Rome. He is the Editorial Coordinator of the Italian Orthopaedic Society Bone Metastasis Study Group of the Italian Orthopaedic Society (S.I.O.T.). He has authored more than 80 manuscripts, and is co-author of the National Guidelines on the management of bone metastases of the S.I.O.T., and of the Italian Association of Medical Oncology (A.I.O.M). He currently is board member of several leading journals in the fields of spine and orthopaedics. Dr. Andrea Piccioli is an orthopaedic surgeon skilled in musculoskeletal oncology, trained at the Memorial Sloan Kettering Cancer Center of New York. He is the Secretary of Italian Society of Orthopedic and Traumatology (S.I.O.T.) and the Coordinator of the Working Group on Bone Metastasis of the Italian Society. He has been Orthopedic Oncologist Consultant in “Palazzo Baleani" Oncologic Unit of Policlinico Umberto I in Rome, and is currently member of the Scientific Committee of the “Istituto Superiore di Sanità”. He is the Director of the 3rd Office for Quality, Clinical Risk and Hospital Program, General Direction of Health Program, National Ministry of Health. He is the author of several scientific papers in the field of orthopaedic oncology and traumatology, and he is also responsible for the S.I.O.T. National Guidelines on Orthopaedic oncology. His main interests are on Musculoskeletal Oncology, and Public Health.