This book covers the following: Applied anatomy of the pterygopalatine fossa and the adjacent structures of the pterygopalatine fossa; Radiological assessment of the pterygopalatine fossa and adjacent structures of the pterygopalatine of the pterygopalatine fossa; Endoscopid transmaxillary biopsy of pterygopalatine fossa masses; Submandibular approach to the pterygopalatine fossa; Transmandibular approach; Facial translocation approach; Aggressive maxillofacial disassembly for treatment of the tumours in the pterygopalatine fosa and adjacent structures of the pterygopalatine fossa; An anterior-lateral approach to extensive tumours in the pterygopalatine extending into the maxillary sinus; subtemporal-preauricular infratemporal fossa approach to large lateral cranial base tumours; Infratemporal middle cranial fossa approach; Endoscopic transnasal approach to the pterygopalantine fossa and Reconstruction of the skull base defects with regional flaps or free flaps. The approach described in each chapter has followed our approach to individual patient. The operative technique sections provides the reader with a step-by-step description of the procedure. It is our intention that this descriptive method will guide the surgeon during the operative procedure.