In Orfeo, composer Peter Els opens the door one evening to find the police on his doorstep. His home microbiology lab—the latest experiment in his lifelong attempt to find music in surprising patterns—has aroused the suspicions of Homeland Security. Panicked by the raid, Els turns fugitive and hatches a plan to transform this disastrous collision with the security state into an unforgettable work of art that will reawaken its audience to the sounds all around it.