Excerpt from Progressive Medicine, a Quarterly Digest of Advances, Discoveries and Improvements in the Medical and Surgical Sciences, Vol. 1: March, 1917; Surgery of the Head and Neck; Surgery of the Thorax, Excluding Diseases of the Breast; Infectious Diseases, Including Acute Rheumatism, Croupous Pneumonia, and Influenza; Diseases of Children; Rhinology, Laryngology and Otology The guinea-pigs operated upon ranged from two days to seven weeks in age. The technic was as follows: A median-line incision was made over the posterior aspect of the skull, the periosteum scraped back with a blunt knife and a chip taken out of the underlying bone down to the dura. The Opening was then enlarged until the superior longitudinal sinus was exposed from its midpoint to its junction with the two lateral sinuses. The removal of the larger part of the occipital bone afforded ample exposure. Of the pineal region. The superior longitudinal sinus was then ligated in two places anterior to the two lateral sinuses and divided with the dura between the ligatures. Upon retracting the posterior flap of dura thus formed, the pineal was exposed, grasped with a mosquito Clamp, and extracted. Great care was necessary to control the subsequent hemorrhage. Control animals were kept under exactly the same conditions, and both sets were sacrificed from seven to fourteen weeks after operation. Careful histological examinations were made of the genital organs and the other endocrine glands. The average weight of the testes of the experimental pigs was almost 200 mg. More than that of the controls, and, microscopically, the tubules were found to be much larger and spermatogenesis more active. Marked differences were also observed in the seminal vesicles, which showed enlarged lumina completely filled by secretion of colloid material. There were no demonstrable differences in the genital organs of the pinealectomized females. By comparing the dates of parturition in the experimental pigs and the controls, it was found to be one-sixth to one-third earlier in the former. In order to eliminate the possibility of the pituitary playing a part in these changes, that organ was examined microscopic ally in the entire series and no change from the normal was demonstrated. The researches of Horrax furnish further evidence in favor of the direct relation between the sexual glands and the pineal during its period of physiological activity. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.