The study on sequential application of herbicides in soybean comprised of 15 treatments viz. Diclosulam 22 g/ha fb Imazethapyr 75 g/ha, Oxyfluorfen 0.1 kg/ha fb Imazethapyr 75 g/ha, Chlorimuron-p-ethyl 9 g/ha fb Imazethapyr 75 g/ha, Diclosulam 22 g/ha fb Quizalofop-p-ethyl 75 g/ha, Oxyfluorfen 0.1 kg/ha fb Quizalofop-p-ethyl 75 g/ha, Chlorimuron-p-ethyl 9g/ha fb Quizalofop-p-ethyl 75 g/ha, Diclosulam 22 g/ha fb Fenoxyprop-p-ethyl 75 g/ha, Oxyfluorfen 0.1 kg/ha fb Fenoxyprop-p-ethyl 75 g/ha, Chlorimuron-p-ethyl 9 g/ha fb Fenoxyprop-p-ethyl 75 g/ha, Imazethapyr 75 g/ha, Quizalofop-p-ethyl 75 g/ha, Fenoxyprop-p-ethyl 75 g/ha, Chlorimuron-p-ethyl 9 g/ha fb Chlorimuron-p-ethyl 9 g/ha, Standard check (Alachlor 2 kg/ha + IC + HW) and Weedy check. The study corroborates that use of sequential use of Oxyfluorfen 0.1 kg/ha fb Imazethapyr 75 g/ha due significantly higher seed yield, net returns and B: C ratio. This treatment was comparable with that of standard check.