Non-Fiction Books:

Statistical Monitoring of Clinical Trials

A Unified Approach
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Description

The approach taken in this book is, to studies monitored over time, what the Central Limit Theorem is to studies with only one analysis. Just as the Central Limit Theorem shows that test statistics involving very different types of clinical trial outcomes are asymptotically normal, this book shows that the joint distribution of the test statistics at different analysis times is asymptotically multivariate normal with the correlation structure of Brownian motion ("the B-value") -- irrespective of the test statistic. Thus, this book offers statisticians an accessible, incremental approach to understanding Brownian motion as related to clinical trials.
Release date Australia
November 19th, 2010
Audience
  • Professional & Vocational
Edition
Softcover reprint of hardcover 1st ed. 2006
Illustrations
32 Illustrations, black and white; XIV, 268 p. 32 illus.
Pages
268
Dimensions
156x234x14
ISBN-13
9781441921345
Product ID
9494227

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