A comprehensive examination of these fascinating proteins. Covers the basic molecular mechanisms of superantigen action, their structure and function, and their role in human diseases. Explains the clinical consequences of superantigen intoxication and the latest therapeutic interventions to combat superantigen toxicity. Emphasizes how newly discovered structural variations among superantigens affect their interactions with human immune cells. Most importantly, these structural and functional differences help explain the exacerbation of certain diseases and why certain superantigens are more effective in some tissues and not in others. Discusses the potential for the use of superantigens in bioterrorism. Serves as essential reading for researchers in the fields of microbiology, immunology, biotechnology, molecular medicine, and clinical infectious disease. This title is published by the American Society of Microbiology Press and distributed by Taylor and Francis in rest of world territories.