Season 5’s horrific finale left Dean (Jensen Ackles) alone, as Sam (Jared
Padalecki) descended into Hell.
Now a different man, Dean vows to stop hunting and devote himself to building
a family. Then, mysteriously, Sam reappears, drawing Dean back into hunting. But
all is not as it seems: Sam is different. A soul-shaking discovery proves
Dean’s suspicions: this is Sam – but not all of him.
As the brothers struggle to reunite, they must also battle deadly
supernatural forces: demons, angels, vampires, shape-shifters. And a terrifying
new foe called the Mother of All.