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This volume describes techniques to make synaptosomes, and discusses numerous ways that synaptosomes are used to study and answer diverse questions about synapses.After examining the history that led to making synaptosomes, the chapters delved into its important as a tool to explore synaptic connections. Some of the topics covered in this book are: synaptosome bioenergetics and glutamate release; affinity proteomics for interactome and phosphoproteome screening in synaptosomes; isolation of highly purified and functionally active synaptic mitochondria; and profiling of microRNA and protein from purified synaptoneurosomes in a neurodegenerative disease model. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and thorough, Synaptosomes is a valuable resource for any researcher interested in learning more about this developing field.
Release date Australia
September 22nd, 2018
Edited by Kathryn M. Murphy
Country of Publication
United States
1st ed. 2018
30 Tables, color; 32 Illustrations, color; 23 Illustrations, black and white; XV, 312 p. 55 illus., 32 illus. in color.
Humana Press Inc.
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