The Chick Embryo Chorioallantoic Membrane in the Study of Angiogenesis and Metastasis

The CAM assay in the study of angiogenesis and metastasis

By:

Domenico Ribatti

Format:

Hardback

Show Hide Adult Content

$268.99

RRP:: ~~$290.95~~ save $21.96

Available from supplier

Usually ships in 3-4 weeks

0 in Trolley

Price Match

Wrap this item as a gift ($5.90) - add a free gift card on the next page

Buy Now, Pay Later with:

4 payments of $67.25 with Afterpay Learn more

Availability

Delivering to:

Estimated arrival:

Around 7-19 June using International Courier

Description

As pointed out by Auerbach in 1991 "Perhaps the most consistent limitation to progress in angiogenesis research has been the availability of simple, reliable, reproducible, quantitative assays of the angiogenesis response." In vitro angiogenesis assays, based on endothelial cell cultures or tissue explant, focus on isolated endothelial cell functions (e.g., endothelial cell proliferation, migration, or invasion) and do not examine the coordination of cell functions required for a successful angiogenic response (Jain et al., 1997; Auerbach et al., 2000). Although in vitro angiogenesis assays have been useful for identi cation of potential molecular targets to block endothelial cell responses and preliminary screening of novel pharmacological agents, they frequently cannot be correlated with in vivo angiogenesis measurements. This is most likely the result of the c- plex and multiple cellular mechanism evoked during new blood vessel formation in vivo. In vitro assays cannot be considered conclusive and the activity of a compound must be con rmed in other assays of increasing complexity, including in vivo assays of angiogenesis, angiogenic-dependent tumor growth, and metastasis.

Release date Australia

February 28th, 2010

Author

Domenico Ribatti

Audience

Professional & Vocational

Illustrations

X, 124 p.

Pages

124

Dimensions

155x235x13

ISBN-13

9789048138432

Product ID

3947615

Customer reviews

Nobody has reviewed this product yet. You could be the first!

Write a Review

Marketplace listings

There are no Marketplace listings available for this product currently.
Already own it? Create a free listing and pay just 9% commission when it sells!

Sell Yours Here