Non-Fiction Books:

The Myth of the Linear, No-Threshold Dose-Response Relationship for Carcinogens


Paperback / softback

Customer rating

Click to share your rating 0 ratings (0.0/5.0 average) Thanks for your vote!

Share this product

The Myth of the Linear, No-Threshold Dose-Response Relationship for Carcinogens by George Parris
34% off
$20.99 was $31.99

Available on orders $100 to $1000. Learn more

In stock with supplier

The item is brand new and in-stock in with one of our preferred suppliers. The item will ship from the Mighty Ape warehouse within the timeframe shown below.

Usually ships within 8-12 days


Delivering to:

Estimated arrival:

  • Around 5-12 November using standard courier delivery


ABSTRACT: The regulatory standards for low-level chemical and radiation exposure in virtually all developed nations are ultimately tied to cancer risk assessment. The risk assessment methodology that has been used most widely for the last 50 years is based on the hypothesis that the probability of cancer is a linear function of dose with no threshold, i.e., the linear, no-threshold (LNT) dose-response hypothesis. Application of this hypothesis to bioassay and/or epidemiological data frequently projects unacceptable risk from minimal exposures. Regulation of chemical and manufacturing industries to conform to these calculated exposures limits is frequently economically burdensome and leads to the abandonment of otherwise technologically attractive products, processes and applications. Moreover, incorporation of these standards into environmental remediation regulations as clean-up standards has frequently required very expensive alternatives for dealing with legacy contamination issues. Thus, many people have challenged the results of LNT analyses. In general, the regulatory agencies and courts have taken the position that the burden of proof is on the plaintiff in these situations and the plaintiff is put into the position of trying to "prove a negative." For practical purposes, this burden is impossible to carry. This manuscript takes a hard look at the origins of the LNT hypothesis and concludes that it is a myth. Literally, the LNT hypothesis was created by application of inappropriate assumptions to questionable data. Basically, the LNT theory never should have been accepted as "science" and should be required to meet a burden-of-proof standard itself in any scientific comparisons. In this manuscript, I will show that the methodology for cancer risk assessment used by regulatory agencies was arbitrarily parsed from the body of scientific literature available circa 1960, because it is simple to apply and inherently over conservative, not because it provided realistic scientific results. This manuscript has 322 citations of the literature.
Release date Australia
July 7th, 2019
Independently Published
Product ID

Customer reviews

Nobody has reviewed this product yet. You could be the first!

Write a Review

Marketplace listings

There are no Marketplace listings available for this product currently.
Already own it? Create a free listing and pay just 9% commission when it sells!

Sell Yours Here

Help & options

  • If you think we've made a mistake or omitted details, please send us your feedback. Send Feedback
  • If you have a question or problem with this product, visit our Help section. Get Help
  • Seen a lower price for this product elsewhere? We'll do our best to beat it. Request a better price
Filed under...