A long-time leader in breast cancer research and therapies at the University of California San Francisco, Dr. Pamela Munster has advised countless women, and their families and loved ones, on how to deal with the unknowns and challenges of this life-altering diagnosis. But when at the age of 48 and otherwise in perfect health, she got a call saying that a routine mammogram showed 'irregularities,' and later learned that she was positive for a BRCA2 mutation, she found herself suddenly, and frighteningly, on the other side of the examining table, a victim of the disease she was an expert in. Weaving together her personal story of treatment and survival after a double-mastectomy, her coming to terms with her father's pancreatic cancer (also related to BRCA), and groundbreaking scientific findings about BRCA and its repercussions throughout the human genome, TWISTING FATE is a refreshing, inspiring, and immensely practical guide to living with BRCA gene mutations. With authority, insight, and compassion, she offers a unique perspective on what it means to have cancer - and how to make informed, yet compassionate, decisions about one's biological fate.