Bartley J. Madden retired as a managing director of Credit Suisse HOLT after a career in investment research and money management that included the founding of Callard Madden & Associates. His early research led to the development of the CFROI valuation framework that is used today by money-management firms worldwide. Madden's current research focuses on knowledge building and wealth creation as opposite sides of the same coin. For additional background information, including journal articles, op-eds, and videos, see his website http: //www.LearningWhatWorks.com. His latest book, Value Creation Thinking, focuses on how creating long-term value begins with clarity about the purpose of the firm and about management's core responsibilities, and emphasizes the overriding importance of a knowledge-building culture. Knowledge building is the topic of his book Reconstructing Your Worldview: The Four Core Beliefs You Need to Solve Complex Business Problems. One idea concerns systems thinking and the identification of key constraints that degrade overall system performance. An application of systems thinking to public policy is reflected in Madden's proposal to restructure the Food and Drug Administration, which is explained in his book Free To Choose Medicine: Better Drugs Sooner at Lower Cost. The fundamental principles of Free To Choose Medicine have already been implemented in Japan for regenerative medicine drugs (see http: //freetochoosemedicine.com).