Evil turns Miami-Dade police detective, Melissa DiMateo's life upside down. All of her police skills can't help her deal with whatever this is and she seeks help from a friend, a Santeria priestess. Together they follow the trail to Louisiana and a Voodoo priestess who is also in trouble with the same man-a powerful and vicious Voodoo priest avoiding criminal charges in the bayou. The women join forces, each using her particular skills to survive a power that would destroy them all.