Kathleen T. Brady, MD, PhD, is Distinguished University Professor and Associate Provost for Clinical and Translational Science at the Medical University of South Carolina. Her interests include drug and alcohol abuse/addiction and comorbid conditions. A board-certified psychiatrist, Dr. Brady leads numerous research projects and served as president of the American Academy of Addiction Psychiatry, a member of the Scientific Advisory Council of the National Institute on Drug Abuse, and a board member of the College on Problems of Drug Dependence. She has authored over 300 publications; presented at conferences, grand rounds, and symposia; and received numerous awards. Sudie E. Back, PhD, a clinical psychologist, is Associate Professor of Psychiatry and Associate Director of the Drug Abuse Research Training program for psychiatry residents at the Medical University of South Carolina. She serves as Principal Investigator or Co-Investigator on numerous federally funded research projects. Her current research involves prescription opioid dependence, the integrated psychosocial treatment of substance use disorders and posttraumatic stress disorder, and gender. The ultimate aim of this line of research is to improve the treatment of individuals with substance use disorders. Dr. Back also maintains a small clinical practice. Shelly F. Greenfield, MD, MPH, is Associate Professor of Psychiatry at Harvard Medical School. She is also Chief Academic Officer and Director of Clinical and Health Services Research and Education, Division of Alcohol and Drug Abuse, McLean Hospital, Belmont, Massachusetts. An award-winning researcher, Dr. Greenfield serves as Principal Investigator and Co-Investigator on federally funded research focusing on treatment for substance use disorders, gender differences in substance disorders, and health services for substance disorders. She is also Director of the Harvard Medical School/Partners Addiction Psychiatry Fellowship and Editor-in-Chief of the Harvard Review of Psychiatry.