Information macrodynamics (IMD) presents the unified information systemic approach with common information language for modelling, analysis and optimization of a variety of interactive processes, such as physical, biological, economical, social, and informational, including human activities. Comparing it with thermodynamics, which deals with transformation energy and represents a theoretical foundation of physical technology, IMD deals with transformation information, and can be considered a theoretical foundation of information computer technology (ICT). ICT includes, but is not limited to, applied computer science, computer information systems, computer and data communications, software engineering, and artificial intelligence. In ICT, information flows from different data sources, and interacts to create new information products. The information flows may interact physically or via their virtual connections, initiating an information dynamic process that can be distributed in space. As in physics, a problem is understanding general regularities of the information processes in terms of information law, for the engineering and technological design, control, optimization, and development of computer technology, operations, manipulations, and management of real information objects. This work belongs to an interdisciplinary science that represents the theoretical and computer-based methodology for system informational description and improvement, including various activities in such interdisciplinary areas as thinking, intelligent processes, management, and other nonphysical subjects with their mutual interactions, informational superimpositions, and the information transferred between interactions.