Call the Midwife meets All Creatures Great and Small in this brand new saga series set in a WWI East End Animal Sanctuary As the Great War engulfs Europe, twenty-one -year old Ruby Archer decides to 'do her bit' at a local munitions factory, quickly making new friends on the deafening factory floor. But wartime is hard for everyone, and she cannot ignore the abandoned animals scavenging in the East End streets. Ruby soon takes in injured terrier Mac, and rescues a stray kitten, Tess, but when all the local cats mysteriously disappear, she knows she needs to do more, and with the help of her friends plans a small-scale monthly clinic. Soon opposition comes from all sides, including her family and the local vet, can Ruby and her friends pull together to show them that in wartime every life matters?