Endocrine Disrupters

Enables researchers to assess the effects of endocrine disrupters as well as comply with new environmental regulations

Endocrine disrupters are chemicals—both man-made and natural—that interfere with the body’s endocrine system, potentially resulting in adverse developmental, reproductive, neurological, and immune effects. In recent years, a number of regulatory authorities around the world have drafted or enacted legislation that requires the detection and assessment of the effects of endocrine disrupters on both humans and wildlife. In response, this book provides comprehensive, up-to-date information on the latest tested and proven methods used to detect and assess the environmental hazards posed by endocrine-disrupting chemicals. Endocrine Disrupters is divided into chapters covering each major taxon as well as chapters dedicated to hazard assessment and regulation. The book covers testing methods for all the vertebrate groups and several invertebrate phyla, including:

Crustaceans and mollusks
Insects
Fish
Amphibians and reptiles
Birds and mammals

Moreover, the book emphasizes practical, ethical testing methods that combine sensitivity, efficiency, statistical power, and reasonable cost. Each chapter is written by one or more international experts in ecotoxicology, offering readers step-by-step guidance for implementing each method based on the latest research and the authors’ firsthand laboratory experience. Furthermore, all the chapters have been subjected to a rigorous peer review and edited in light of the reviewers’ comments. References at the end of each chapter guide readers to the literature in the field. Endocrine Disrupters is recommended for scientists who need to test chemicals for possible endocrine-disrupting properties. It is also recommended for regulatory authorities who need to decide whether particular chemicals can be safely marketed.

Author Biography

PETER MATTHIESSEN, PhD, is an aquatic ecotoxicologist whoworks as an independent consultant. Specializing in the study ofendocrine disrupters, he has conducted extensive research into howsewage effluents cause feminization in wild male fish as well ashow tributyltin-based antifoulants cause masculinization in wildfemale mollusks. Professor Matthiessen is a member of the UKAdvisory Committee on Pesticides and Co-chair of the OECDValidation Management Group for Ecotoxicity Tests. He hascontributed to the development of standardized ecotoxicity assayswith sensitivity for endocrine disrupters as well as writtenguidance for the interpretation of the resulting data.