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Essential for the laboratory, this practical manual presents a wide variety of techniques associated with the use of human CNS tissue obtained at autopsy. The book contains detailed methodologies in discrete chapters written by an expert in the specific field. It also addresses the potential for extending molecular studies in brain tissue obtained at autopsy into studies in living brain by using neuroimaging techniques. In addition, the reader is directed to suppliers of equipment and reagents that have been shown to be useful when studying human brain tissue. Topics include problems of collecting brain tissue at autopsy, how psychiatric diagnosis can be made after death and specific problems faced in using human brain tissue in modern laboratory-based techniques. Suitable for all those using human tissue in their research, this manual is of particular value to those commencing studies using human brain tissue. Those involved in the study of brain tissue in an attempt to understand m
Author Biography
Brian Dean, Mental Health Research Institute of Victoria, Parkville, Australia. Thomas M Hyde, Joel E Kleinman, both National Institute of Mental Health, Washington DC, USA.
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