Alice Howland is a brilliant woman who is given the devastating diagnosis of early onset Alzheimer's at age 50. This heartfelt drama illustrates Alice's life as a linguistics professor at Columbia University and her rapid decline of words, sentences and sense of self. On a day like any other, Alice sets out for a run, taking the route she always runs and soon realises she has no idea how to find her way home. She is lost – a feeling that will only grow for her and those around her.
- Winner of an Academy Award for Best Actress (Julianne Moore)
- Winner of a Golden Globe for Best Actress in a Motion Picture, Drama (Julianne Moore)
- Winner of a BAFTA Award for Best Actress in a Leading Role (Julianne Moore)
- Winner of a SAG Award for Best Actress (Julianne Moore)
- Winner of a Critics Choice Award for Best Actress (Julianne Moore)