Water utilities are being required to provide higher levels of disinfection while also reducing the concentrations of disinfection by-products. One new technology for meeting these goals is the MIEXTM process for removing dissolved organic carbon (DOC). This process may also work well in conjunction with coagulation by both reducing the dose of coagulant needed and by working in combination to achieve a higher level of NOM removal than is available with either process separately. The primary objectives of this project were to evaluate the MIEXTM process under different water quality conditions to demonstrate its applicability for the removal of naturally occurring matter (NOM) and for control of disinfection by-product formation. Testing was also conducted to assess removal of selected inorganic anions. Results of the full-scale operation at the Wanneroo Groundwater Treatment Plant in Western Australia (WGTP) are also discussed to develop additional guidance for planning and implementation based on actual conditions of operation.