Non-Fiction Books:

Human Papillomavirus (HPV) Involvement in Esophageal Carcinogensis

Format

Paperback

Customer rating

Click to share your rating 0 ratings (0.0/5.0 average) Thanks for your vote!

Share this product

Human Papillomavirus (HPV) Involvement in Esophageal Carcinogensis by Kari Syrjanen
Unavailable
Sorry, this product is not currently available to order

Description

Esophageal squamous cell carcinoma (SCC) has a peculiar geographical distribution, with up to 500-fold variations in incidence between the low- and high-risk regions. The first reports suggesting HPV involvement in both benign and malignant squamous cell tumours of the oesophagus date back to 1982. The rapidly increasing literature on this subject is summarised in this book. Screening studies in high-incidence areas of China using balloon cytology sampling report high prevalence of HPV DNA among asymptomatic subjects, followed by HPV DNA detection in hyperplastic and dysplastic epithelia adjacent to SCC. There are close human parallels to both SCP and SCC in the cattle, linked with BPV4 and alimentary carcinogens (bracken fern). In vitro experiments on HPV-positive cancer cell lines implicate similar molecular mechanisms as involved e.g. in HPV-associated genital carcinogenesis. Taken together, these data suggest that the (multifactorial) etiology of oesophageal cancer differs between the low- and high-incidence geographical areas. Oncogenic HPV types seem to play an important causal role only in the high-incidence regions.
Release date Australia
August 19th, 2010
Author
Country of Publication
United States
Illustrations
tables
Imprint
Nova Science Publishers Inc
Pages
96
ISBN-13
9781608762118
Product ID
3420929

Customer reviews

Nobody has reviewed this product yet. You could be the first!

Write a Review

Marketplace listings

There are no Marketplace listings available for this product currently.
Already own it? Create a free listing and pay just 9% commission when it sells!

Sell Yours Here

Help & options

  • If you think we've made a mistake or omitted details, please send us your feedback. Send Feedback
  • If you have a question or problem with this product, visit our Help section. Get Help
Filed under...