Non-Fiction Books:

Repliement de La Sequence Polypeptidique Des Petites Proteines

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Paperback

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Repliement de La Sequence Polypeptidique Des Petites Proteines by Campbell-Valois Francois-Xavier
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Description

Dans cet ouvrage, les notions de base en biologie structurale du repliement des proteines sont presentees dans une perspective historique et theorique. Dans la seconde partie, les resultats de nos travaux sur le repliement du domaine liant Ras de la proteine Raf sont decrits. En bref, nous avons utilise une approche de librairies de codons degeneres pour comprendre les determinants de sequence du repliement de ce petit domaine proteique qui adoptent la topologie d'ubiquitine. Par la suite, nous avons utilise des approches biophysiques classiques afin de comprendre les mecanismes de repliement et de stabilisation de la structure du DLR de Raf, en prenant soin de constamment comparer nos resultats aux donnees rapportees dans la litterature pour des analogues structuraux, soit principalement l'ubiquitine. Finalement, le livre se termine sur une discussion generale et personnelle de l'auteur sur l'avenir de la recherche en repliement des proteines."
Release date Australia
December 22nd, 2014
Country of Publication
United States
Illustrations
black & white illustrations
Imprint
Presses Academiques Francophones
Pages
212
Dimensions
152x229x12
ISBN-13
9783838147468
Product ID
23705895

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