Bonobo Bob and Billie Ape lead the other animals living at the zoo in Zoological Operations Organization, which is referred to as "ZOO." ZOO is made up of Fancy and Freddy Fox, Montee Monkey, Reynaldo Raccoon, Willie Wombat, Redtail Rick, Bobo Bigfoot, and an assist from Goldie golden Lab as well as plenty of others. The animals use their natural abilities, skills, and sense of humor to benefit the other animals and humans of the zoo and the surrounding area. Bonobo Bob and Billie Ape also educate the group on the relationship various animals have with humans. All while Hopper Rabbit tries not to get eaten.