Todd Leff is Associate Professor in the Department of Pathology at the Wayne State University School of Medicine in Detroit, Michigan. In 1991 he moved to the Parke-Davis Company where he became the Director of the Transcription Research Group in the Department of Cell biology. In 2002 he joined the faculty at the Wayne State. He serves on the editorial boards of the Journal of Biological Chemistry, the Journal of Lipid Research and the American Journal of Physiology. James Granneman is Professor of Psychiatry and Behavioral Neurosciences, and Pathology at Wayne State University School of Medicine. Dr. Granneman's research interests include lipolysis and adrenergic signal transduction in adipose tissues, and he serves on the editorial board of American Journal of Physiology.