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Advancing Methods for Biomolecular Crystallography

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Description

This work presents a snapshot of the state of the art of modern biomolecular crystallography, from crystallisation through structure determination and even interactive presentation on the web.  Methods driving the latest automated structure determination pipelines are explained, as well as how to deal with problems such as crystal pathologies that still demand expert analysis.  These methods are illustrated through their application to problems of great biological interest, such as the molecular machinery underlying the complement pathway, the mechanism of action of monoamine oxidase inhibitors, and the structure of the eukaryotic ribosome.  Complementary approaches, such as neutron diffraction, small angle X-ray scattering, coherent diffraction and computational modelling, are also explored.
Release date Australia
April 16th, 2013
Audience
  • Professional & Vocational
Contributors
  • Edited by Alexandre G. Urzhumtsev
  • Edited by Randy Read
  • Edited by Vladimir Y. Lunin
Illustrations
131 Illustrations, black and white; XIII, 362 p. 131 illus.
Pages
362
Dimensions
156x234x19
ISBN-13
9789400763197
Product ID
21042037

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