5-Way Optimization: One-click, system-wide tuning, delivering optimized overclocks and intelligent cooling for CPU or GPU-intensive tasks.
Industry-leading cooling options: Comprehensive controls for fans and water pumps, via Fan Xpert 4 software or the acclaimed ASUS UEFI.
M.2 heatsink: Ultra-efficient heatsink reduces M.2 SSD temperatures by up to 20°C for unthrottled SSD storage speeds and enhanced reliability.
Aura Sync: Controllable onboard RGB lighting that’s easily synced with an ever-growing portfolio of Aura-capable hardware.

ASUS Prime X299-A is the ATX motherboard that's been expertly engineered for professional content creators and power users who work hard by day and play harder by night. This powerful, innovative board puts a friendly face on advanced enthusiast controls, enabling you to maximize performance, cooling and personalization with ease. So, if you live to create, to explore, to enjoy and to push the boundaries, look no further than Prime X299-A.

5-Way Optimization
One-click overclock and cooling, done!
One click takes care of all that complex tuning. ASUS 5-Way Optimization makes your PC smart. It dynamically optimizes essential aspects of the system, providing overclocking and cooling profiles that are tailored for your rig.

An automated tuning utility that optimizes overclocking and cooling profiles for your unique system configuration.
Fans stay whisper-quiet for everyday computing, and deliver optimal airflow when the system is crunching through CPU or GPU-intensive tasks.
All-new stress test that allows users to optimize and overclock for CPU or memory-centric workloads.

Media-acclaimed UEFI BIOS
The smoothest, slickest mouse-controlled graphical BIOS has been improved to make it even more appealing. Whether you're a PC novice or a seasoned overclocker, the EZ and Advanced Modes help you find your way, quickly and easily.

Make your memory go faster
With optimized trace paths for time-aligned signaling and minimal crosstalk, Third-generation ASUS T-Topology offers enhanced memory stability and compatibility, allowing support for memory speeds of DDR4–4133 MHz and beyond.

OC design- ASUS PRO Clock II technology
A dedicated base-clock generator that extends CPU and memory overclocking margins. This custom solution works in tandem with the TPU to enhance voltage and base-clock overclocking control, providing the flexibility to extract every ounce of performance from Intel® Core™ X-series processors.

M.2
Speed up with onboard M.2 up to 32Gbps
With x4 PCI Express 3.0/2.0 bandwidth, M.2 supports up to 32Gbps data-transfer speeds. It is the perfect choice for an operating system or application drive, providing fast access to data.

M.2 heatsink
Keep your SSD cooler
Prime X299-A has an ultra-efficient heatsink to reduce M.2 SSD temperatures by up to 20°C — and that means optimal storage performance and improved SSD longevity.

VROC
Upgrade your RAID
Unleash the Prime X299-A Virtual RAID on CPU (VROC) feature with the addition of an ASUS Hyper M.2 X16 Card*, which allows you to attach up to four PCIe® 3.0 x16 M.2 drives — for a total bandwidth of up to 128Gbps. With VROC, you can utilize CPU PCIe lanes to configure a bootable RAID array, eliminating traditional DMI bottlenecks, so that storage transfers aren't held back by other traffic.

Intel Optane memory
Intel Optane memory ready
Intel Optane™ is a revolutionary non-volatile memory technology supported by Prime X299-A. Intel Optane memory modules accelerate attached storage to reduce boot and load times, so everything feels faster and more responsive.

ThunderboltEX 3 Card
Experience blistering ThunderboltTM 3 speeds and any-way-up connectivity
Prime X299-A offers support for ThunderboltEX 3 card, an Intel-certified Thunderbolt™ 3 add-on card enables breathtaking bi-directional speeds of up to 40Gbps through a single cable — up to 4X faster than other PC data-transfer protocols. Beyond sheer bandwidth, Thunderbolt 3 supports daisy-chaining up to six devices; utilizes a Type-C reversible connector for compatibility with the latest USB 3.1 Gen 2 Type-C devices; and supports the USB Power Delivery specification for fast, high-power charging of up to 36W.

Intel Ethernet
More throughput, less CPU usage and great gaming experiences
Prime X299-A features the latest Intel Ethernet. Intel's LAN has the advantage of reducing CPU overhead and offering exceptionally high TCP and UDP throughput for faster, smoother data transfer.

Multi-GPU support
With support for both NVIDIA® SLI™ and AMD CrossFireX™ 2/3-WAY configurations, Prime X299-A motherboard enables multi-GPU setups so you can harness the full power of the latest graphics technologies to drive games at 4K and beyond.

SafeSlot
Protect your Graphics Card Investment
SafeSlot* is the PCIe slot reinvented by ASUS and engineered to provide superior retention and shearing resistance. Manufactured in a single step using a new insert-molding process, SafeSlot integrates the slot with fortifying metal for an inherently stronger slot, which is then firmly anchored to the PCB through additional solder points.

Outstanding audio
Realtek codec and unique design features for pristine, powerful audio

Prime X299-A utilizes a unique audio codec designed in close collaboration with Realtek — the Realtek S1220A. It also features an unprecedented 120dB signal-to-noise ratio for the stereo line-out and a 113dB SNR for the line-in, providing pristine audio quality. Additionally, a new impedance-sensing circuit automatically adjusts gain to ensure the optimal volume range for your headphones.

DTS Headphone:XTM
Surround sound, to go
Immersive 3D surround-sound technology provides incredible audio experiences.

Crystal Sound 3
Flawless audio that makes you part of the game

Power pre-regulator
Reduces power-input noise to ensure consistent performance.

Audio shielding
Separates analog/digital signal domains, significantly reducing multi-lateral interference.

Separate layer for left and right tracks
Ensures minimal crosstalk between audio paths.

Integrated amplifier
Capable of driving high-impedance headphones, without rolling-off high or low frequencies.

De-pop circuit
Reduces start-up popping noise to all audio outputs.

Premium Japanese-made audio capacitors
Premium parts provide an immersive sound signature, with exceptional fidelity.

Aura Sync
Outshine your competition
A well-tuned enthusiast system deserves a matching aesthetic. ASUS Aura offers full RGB lighting control with a variety of functional presets for the built-in RGB LEDs as well as strips connected to the onboard RGB headers.* And it can all be synced with an ever-growing portfolio of Aura-capable ASUS hardware.

Exclusive 3D mount for easy installation
Make it your own
Dedicated 3D mounts on the motherboard makes fitting 3D-printed parts easy. Using the same screws as M.2 drives and standard motherboard mounting holes, you can easily add nameplates and cable covers.

CPU
Intel® Socket 2066 Core™ X-Series Processors

• The Intel® Turbo Boost Max Technology 3.0 support depends on the CPU types
• Refer to www.asus.com for CPU support list

Chipset
Intel® X299

Memory
Intel® Core™ X-series Processors (6-core above)
8 x DIMM, Max. 128GB, DDR4 4000(O.C­.)/3600(O.C.)/2666/2400­/2133 MHz Non-ECC, Un-buffered Memory
Intel® Core™ X-series Processors (4-core)
4 x DIMM, Max. 64GB, DDR4 4000(O.C­.)/3600(O.C.)/2666/2400­/2133 MHz Non-ECC, Un-buffered Memory

• Hyper DIMM support is subject to the physical characteristics of individual CPUs.
• Refer to www.asus.com for the Memory QVL (Qualified Vendors Lists).

Multi-GPU Support
Supports NVIDIA® Quad-GPU SLI™ Technology
Supports NVIDIA® 3-Way SLI™ Technology
Supports NVIDIA® 2-Way SLI™ Technology
Supports AMD Quad-GPU CrossFireX™ Technology
Supports AMD 3-Way CrossFireX™ Technology

Expansion Slots
44-Lane CPU-
3 x PCIe 3.0/2.0 x16 (x16, x16/x16, x16/x16/x8)
2 x PCIe 3.0 x4 (max at x4 mode) *1
1 x PCIe 3.0/2.0 x1 *3
28-Lane CPU-
3 x PCIe 3.0/2.0 x16 (x16, x16/x8, x16/x8/x1) *4
2 x PCIe 3.0 x4 (max at x4 mode) *1
1 x PCIe 3.0/2.0 x1 *3
16-Lane CPU-
3 x PCIe 3.0/2.0 x16 (x16, x8/x8, x8/x8/x1) *4
2 x PCIe 3.0 x4 (max at x4 mode) *1
1 x PCIe 3.0/2.0 x1 *3

Storage
Intel® X299 Chipset :
1 x M.2 x4 Socket 3, with M key, type 2242/2260/2280 storage devices support (SATA & PCIE 3.0 × 4 mode)
1 x M.2 x4 Socket 3, with M key, type 2242/2260/228­0/22110 storage devices support (PCIE 3.0 × 4 mode)
8 x SATA 6Gb/s port(s)
Support Raid 0, 1, 5, 10
Supports Intel® Smart Response Technology, Intel Rapid Start Technology
Intel® Optane™ Memory Ready

LAN
Intel® I219V, 1 x Gigabit LAN Controller(s), featuring Turbo LAN
ASUS Turbo LAN Utility
ASUS LAN Guard

Audio
Realtek® ALC S1220A 8-Channel High Definition Audio CODEC

• Impedance sense for front and rear headphone outputs
• Internal audio Amplifier to enhance the highest quality sound for headphone and speakers
• Supports : Jack-detection, Multi-streaming, Front Panel Jack-retasking

Audio Feature :

• DTS Connect
• DTS Headphone:X
• Optical S/PDIF out port(s) at back panel
• Audio Shielding: Ensures precision analog/digital separation and greatly reduced multi-lateral interference
• Dedicated audio PCB layers: Separate layers for left and right channels to guard the quality of the sensitive audio signals
• Premium Japanese-made audio capacitors: Provide warm, natural and immersive sound with exceptional clarity and fidelity
• Unique de-pop circuit: Reduces start-up popping noise to audio outputs
• EMI protection cover to prevent electrical noise to affect the amplifier quality

Separate layer for left and right track, ensuring both sound deliver equal quality

USB Ports
ASMedia® USB 3.1 Gen 2 controller :
1 x USB 3.1 Gen 2 port(s) (1 at mid-board)
ASMedia® USB 3.1 Gen 2 controller :
2 x USB 3.1 Gen 2 port(s) (Type-A + USB Type-CTM)
Intel® X299 Chipset :
8 x USB 3.1 Gen 1 port(s) (4 at back panel, , 4 at mid-board)
Intel® X299 Chipset :
4 x USB 2.0 port(s) (4 at back panel, , 2 at mid-board)

Special Features
OC Design – ASUS PRO Clock II Technology
ASUS Dual Intelligent Processors 5-Way Optimization by Dual Intelligent Processors 5 :

• 5-Way Optimization tuning key perfectly consolidates TPU, EPU, DIGI+ VRM, Fan Xpert 4, and Turbo Core App

AURA :

• Aura RGB Strip Headers
• Aura Lighting Effects Synchronization with compatible ASUS ROG devices

ASUS Exclusive Features :

• USB BIOS Flashback
• MemOK!
• AI Suite 3
• Ai Charger
• Onboard Button : Power
• ASUS UEFI BIOS EZ Mode featuring friendly graphics user interface
• Turbo LAN
• Crystal Sound 3

File Transfer

• Cloud GO!
• File Transfer

ASUS EZ DIY :

• ASUS EZ Flash 3
• ASUS USB BIOS Flashback
• ASUS UEFI BIOS EZ Mode
• Multi-language BIOS

ASUS Q-Design :

• ASUS Q-Shield
• ASUS Q-Code
• ASUS Q-LED (CPU, DRAM, VGA, Boot Device LED, HDD LED)
• ASUS Q-Slot
• ASUS Q-DIMM
• ASUS Q-Connector

Gaming Aesthetics :

• 3D printing friendly
• AURA-RGB Lighting

M.2 Onboard(The latest transfer technologies with up to 32Gb/s data transfer speeds)

Back I/O Ports
1 x LAN (RJ45) port(s)
2 x USB 3.1 Gen 2 Type-A + USB Type-CTM
4 x USB 3.1 Gen 1
2 x USB 2.0 (one port can be switched to USB BIOS Flashback)
1 x Optical S/PDIF out
5 x Audio jack(s)
1 x USB BIOS Flashback Button(s)

Internal I/O Ports
1 x AAFP connector
2 x Aura RGB Strip Header
2 x USB 3.1 Gen 1 connector(s) support(s) additional 4 USB 3.1 Gen 1 port(s)
1 x USB 2.0 connector(s) support(s) additional 2 USB 2.0 port(s)
1 x M.2 Socket 3 with M key, type 2242/2260/2280 storage devices support (SATA & PCIE 3.0 × 4 mode)
1 x M.2 Socket 3 with M key, type 2242/2260/228­0/22110 storage devices support (PCIE 3.0 × 4 mode)
8 x SATA 6Gb/s connector(s)
1 x M.2_FAN connector
1 x VROC_HW_Key
1 x CPU Fan connector(s)
1 x CPU OPT Fan connector(s)
2 x Chassis Fan connector(s)
1 x AIO_PUMP connector
1 x W_PUMP+ connector
1 x Thunderbolt header(s)
1 × 24-pin EATX Power connector(s)
1 × 8-pin ATX 12V Power connector(s)
1 × 4-pin ATX 12V Power connector(s)
1 x System panel(s) (Q-Connector)
1 × 5-pin EXT_FAN(Extension Fan) connector
1 x MemOK! button(s)
1 x Thermal sensor connector(s)
1 x Power-on button(s)
1 x Clear CMOS jumper(s)
1 x USB 3.1 Gen 2 front panel connector
1 x CPU_OV jumper

Accessories
User's manual
ASUS Q-Shield
1 x Vertical M.2 bracket set
4 x SATA 6Gb/s cable(s)
1 x M.2 Screw Package
1 x Supporting DVD
1 x SLI HB BRIDGE(2-WAY-M)
1 x Q-Connector

BIOS
128 Mb Flash ROM, UEFI AMI BIOS, PnP, DMI3.0, WfM2.0, SM BIOS 3.0, ACPI 6.0, Multi-language BIOS,
ASUS EZ Flash 3, CrashFree BIOS 3, F11 EZ Tuning Wizard, F6 Qfan Control, F3 My Favorites, Last Modified log, F12 PrintScreen and ASUS DRAM SPD (Serial Presence Detect) memory information

Manageability
WfM 2.0, DMI 3.0, WOL by PME, PXE
Support Disc
Drivers
ASUS Utilities
EZ Update
Anti-virus software (OEM version)

Operating System
Windows® 10 64-bit

Form Factor
ATX Form Factor
12 inch x 9.6 inch ( 30.5 cm x 24.4 cm )
Note

1. PCIEX4_1 max. at x1 mode, PCIEX4_2 max. at x4 mode
2. SATA6G₅/6/7/8 share bandwidth with PCIEX4_2.
3. PCIEX1_1 shares bandwidth with Front USB 3.1 GEN 2
4. PCIEX16_3 share bandwidth with PCIEX4_1 when using x28 or x16 lane CPU