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Calcium Channel Pharmacology
Calcium Channel Pharmacology
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Calcium Channel Pharmacology

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Description

Voltage-gated calcium channels are critical regulators of cytoplasmic levels of calcium, the universal signaling ion. As such, calcium channels trigger a wide range of cellular functions, from muscle contraction to neurotransmitter secretion, and are important players in human disease. Prominent in the nervous, cardiovascular, and endocrine systems, members of the calcium channel family are targets for existing antihypertensive and anticonvulsant drugs. In addition, they are emerging targets for drugs to treat an extraordinarily diverse group of disorders, including pain, cerebral ischemia, cardiac arrhythmia, and migraine. This book reviews the compounds that target individual calcium channel subtypes and the cellular and behavioral functions governed by each different channel. It contains information for basic scientists using calcium channel antagonists as experimental tools, for behavioralists studying animal models of human disease, and for pharmaceutical scientists interested in creating the next generation of calcium channel-targeted drugs. Several factors make an entire book on calcium channel pharmacology timely.
Release date Australia
September 15th, 2012
Audience
  • Professional & Vocational
Contributor
  • Edited by Stefan I. McDonough
Edition
Softcover reprint of the original 1st ed. 2004
Illustrations
XV, 418 p.
Pages
418
Dimensions
178x254x23
ISBN-13
9781461348603
Product ID
21700462

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