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Camptothecins in Cancer Therapy
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Camptothecins in Cancer Therapy

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Description

A critical review our current understanding of camptothecins, their shortcomings, and of the possibilities for improving their clinical performance. The authors discuss new camptothecin analog development, drug delivery issues for optimizing their anticancer activity, and their potential use in a variety of different cancers. Additional chapters describe what is known about the biochemistry, the pharmacology, and the chemistry of the camptothecins, including the mechanism of topoisomerase and how camptothecins poison this enzyme, the use of animal models in defining the anticancer potential of camptothecins, and the question of camptothecin resistance.
Release date Australia
November 15th, 2014
Audience
  • Professional & Vocational
Contributor
  • Edited by Val R. Adams
Illustrations
XIII, 460 p.
Pages
460
Dimensions
155x235x24
ISBN-13
9781627038164
Product ID
23745338

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