In the 21st century, social media has emerged as a pivotal force shaping business strategies and entrepreneurship. The rapid evolution of social media platforms poses a pressing question: how can one effectively address this fast-paced transformation? Cases on Social Media and Entrepreneurship explores this and delves into media entrepreneurship, giving special attention to its role in developing women entrepreneurs. It skillfully tackles the challenge of gender disparities within the entrepreneurial landscape. Simultaneously, it also explores how to harness the power of artificial intelligence amid the integration challenges it presents, offering instrumental insights for entrepreneurs and investors, stakeholders, government officials, and policymakers. A historical perspective of media entrepreneurship unfolds, providing a foundational understanding of its evolution. With the advent of artificial intelligence (AI), the narrative progresses to establishing an AI-based social media entrepreneurship system, unveiling the transformative potential of technology. Real industry analyses are presented through enlightening case studies, uncovering various issues, and offering viable solutions. This unique approach enhances entrepreneurial knowledge and skills, empowering practitioners to confidently navigate the complex social media landscape. The book does not stop at identifying challenges; it propels the discourse forward by exploring the future of social media entrepreneurship in business. Addressing AI-related concerns, the book investigates whether it threatens social media entrepreneurs or opens up new avenues for growth. Themes like poverty alleviation, the impact on advertising costs, and the intersection of social media entrepreneurship with AI-driven advancements are thoroughly examined.