Non-Fiction Books:

Coarse-Grained Modelling of DNA and DNA Self-Assembly

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Hardback
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Description

This thesis presents a novel coarse-grained model of DNA, in which bases are represented as rigid nucleotides. The model is shown to quantitatively reproduce many phenomena, including elastic properties of the double-stranded state, hairpin formation in single strands and hybridization of pairs of strands to form duplexes, the first time such a wide range of properties has been captured by a coarse-grained model. The scope and potential of the model is demonstrated by simulating DNA tweezers, an iconic nanodevice, and a two-footed DNA walker — the first time that coarse-grained modelling has been applied to dynamic DNA nanotechnology.
Release date Australia
July 7th, 2012
Audience
  • Professional & Vocational
Illustrations
xii, 176 p.
Pages
176
Dimensions
155x235x15
ISBN-13
9783642305160
Product ID
20222241

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