This book constitutes the refereed proceedings of the 19th IFIP WG 5.5 Working Conference on Virtual Enterprises, PRO-VE 2018, held in Cardiff, UK, in September 2018.  The 57 revised full papers were carefully reviewed and selected from 143 submissions. They provide a comprehensive overview of identified challenges and recent advances in various collaborative network (CN) domains and their applications, with a strong focus on the following areas: blockchain in collaborative networks, industry transformation and innovation, semantics in networks of cognitive systems, cognitive systems for resilience management, collaborative energy services in smart cities, cognitive systems in agribusiness, building information modeling, industry 4.0 support frameworks, health and social welfare services, risk, privacy and security, collaboration platform issues, sensing, smart and sustainable enterprises, information systems integration, dynamic logistics networks, collaborative business processes, value creation in networks, users and organizations profiling, and collaborative business strategies.