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Crystallization of Organic Compounds

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Crystallization of Organic Compounds

An Industrial Perspective
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Description

This book summarizes crystallization methodologies that have been developed and/or observed by the authors during their employment as Process Engineers in the Chemical Engineering Research & Development Department of the Merck Research Laboratories Division. Analysis covers the four major methods of carrying out crystallization operations, their strengths and potential issues, as well as numerous examples of crystallization processes from development through manufacturing scale. The book focuses primarily on the authors' experiences with various crystallization operations through the use of examples as well as a summary of these experiences in guiding development and scale-up.

Author Biography:

Hsien-Hsin Tung, PhD, was a senior investigator in Pharmaceutical Research & Development for Merck Research Laboratories until his retirement. Dr. Tung founded the Crystallization Laboratory in Chemical Engineering Research & Development, Merck Research Laboratories. Edward L. Paul, PhD, is retired director of Chemical Engineering Research & Development at Merck Research Laboratories. In addition to numerous patents and publications, Dr. Paul was coauthor of several chapters in, and senior editor of, the Handbook of Industrial Mixing: Science and Practice (Wiley). Michael Midler, PhD, is retired senior investigator, Chemical Engineering, with Merck Research Laboratories. His more recent patents and publications are primarily in processes for crystallization and the mixing of liquids. Dr. Midler coauthored, with Dr. Paul, "Mixing in the Fine Chemicals and Pharmaceutical Industries," in the Handbook of Industrial Mixing: Science and Practice. James A. Mccauley, PhD, was a senior investigator in the Analytical Research Department for Merck Research Laboratories until his retirement. After that, he served as an adjunct professor for the Pharmaceutical Engineering Training Program in the Department of Chemical and Biochemical Engineering at Rutgers University.
Release date Australia
July 3rd, 2009
Audiences
  • Professional & Vocational
  • Tertiary Education (US: College)
Pages
300
Dimensions
184x260x18
ISBN-13
9780471467809
Product ID
2771267

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