After finding his family murdered, Matthew Burke is arrested and sentenced to life in prison. The next day he is mysteriously released and given a briefcase of money. Needing answers, Matthew finds a pile of old documents in his house and discovers his wife was once part of an organization called D.R.E.X, who were responsible for hunting and killing supernatural creatures. Even though D.R.E.X had been shut down for years, his wife was murdered just after she tried to reach them. Matthew reluctantly joins with the remnants of her old organization and investigates a new problem arising in France. But the more he discovers, the more he realizes how few people he can trust...