Large-scale information systems in public utility services depend on computing infrastructure. Many research e?orts are being made in related areas, such as mobile computing, cloud computing, sensor networks, high-level user interfaces and information accesses by Web users. Government agencies in many countries plan to launch facilities in education, health-care and information support as a part of e-government initiative. In this context, information interchange m- agement has become an active research ?eld. A number of new opportunities have evolved in design and modeling based on the new computing needs of the users. Database systems play a centralrole in supporting networkedinformation systems for access and storage management aspects. The 6thinternationalworkshoponDatabasesin NetworkedInformationS- tems (DNIS) 2010 was held during March 29-31, 2010 at University of Aizu in Japan. The workshop program included research contributions and invited c- tributions. A view of research activity in information interchange management and related research issues was provided by the sessions on related topics. The keynoteaddresswascontributedbyDivyakantAgrawal. Theworkshopsessionon "NetworkedInformationSystems:Infrastructure"had invitedpapersbyHarumi KunoandMaluCastellanos. Thesessionon"AccessestoInformationResources" had an invited contribution from Joachim Biskup. The following section on "Information and Knowledge Management Systems" included invited contri- tions from Toyoaki Nishida and Tetsuo Kinoshita. The session on "Information Extraction from Data Resources" included the invited contribution of Polepalli Krishna Reddy. The section on "Geospatial Decision Making" comprised c- tributions by Cyrus Shahabi and Yoshiharu Ishikawa. We would like to thank the members of the Program Committee for their support and all authors who contributed to DNIS 2010.