As the world population is expanding and resources are shrinking it creates a challenging environment for people in low income and transitioning economies as well as developed countries. Hence, researchers are proposing different solutions and entrepreneurship is one of them. Academic institutions need to update their study programs and knowledge, modernize the curriculum and integrate research activities in degree programs about entrepreneurship. Economic challenges are getting very difficult to handle for every country and entrepreneurship can play a key role in dealing with these new realities. Aspects of academic entrepreneurship and entrepreneurial education unlock the discussion about the concepts, risks, actions and approaches towards the entrepreneurial university. Academic entrepreneurship focuses on the educated population who are learning and working in the universities and how they can create an entrepreneurial ecosystem so that academia can play forth the role of entrepreneurship after teaching and research. This book will contribute to the knowledge on developing an entrepreneurial ecosystem through academia. The target audience are university teachers, students, and researchers. This book will be appropriate for universities and policy makers to adopt and apply entrepreneurial approaches to develop academic entrepreneurship and an entrepreneurship ecosystem.