In this issue of Immunology and Allergy Clinics, guest editors Drs. Glenn T. Furuta and Dan Atkins bring their considerable expertise to the topic of Eosinophilic Gastrointestinal Diseases. Top experts provide a multilayered examination of the current state of knowledge in the field, compiling an issue that serves as a convenient reference for the evaluation and management of eosinophilic esophagitis (EoE) and eosinophilic gastrointestinal diseases (EGIDs). Contains 21 relevant, practice-oriented topics including epidemiological and clinical clues to the etiology of EoE; dietary management of EoE; quality of life with EoE; diversity, equity, and inclusion in EoE; clinical presentation of patients with EGIDs; pharmacologic management of EGIDs; and more. Provides in-depth clinical reviews on eosinophilic gastrointestinal diseases, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.