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Experimental Models of Parkinson’s Disease
Experimental Models of Parkinson’s Disease
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Experimental Models of Parkinson’s Disease

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Description

This detailed book focuses on cutting-edge methods for Parkinson’s disease (PD) research, such as the analysis of the prion-like properties of α-synuclein, mitochondrial functions related to the PINK1-Parkin pathway/CHCHD2, the endolysosome pathway related to LRRK2, VPS35, and ATP13A2 using cultured cells (including patient iPS cells), deep brain stimulation therapy, classic mitochondrial toxins related to PD, and genetic associations and screenings using mammalian and invertebrate genetic models of PD. The collection intends to serve as an introductory protocol book for basic research on PD pathogenesis. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.  Authoritative and practical, Experimental Models of Parkinson's Disease is an ideal guide for researchers continuing to work toward making PD risk predictable and surmountable.
Release date Australia
May 29th, 2022
Audiences
  • Postgraduate, Research & Scholarly
  • Professional & Vocational
Contributor
  • Edited by Yuzuru Imai
Edition
1st ed. 2021
Illustrations
47 Illustrations, color; 10 Illustrations, black and white; XI, 217 p. 57 illus., 47 illus. in color.
Pages
217
ISBN-13
9781071614976
Product ID
35844371

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