This publication explains the principles that underlay strong ground motion simulation, describes various methods for simulating strong ground motions, and shows some examples of strong ground motion simulations using fault rupture modelling. The detailed guidelines and practical tools presented in this Safety Report will be of value to researchers, operating organizations, regulatory bodies, vendors and technical support organizations in the areas of seismic hazard evaluation of nuclear installations. The information provided will also be of great importance for seismic hazard assessments following the Fukushima Daiichi NPP accident.